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Core Strategy
Seek
ADAR-Expressing Tissues
Guided by endogenous editing levels and gene expression
Utilize
Existing Technologies
Avoid reinventing delivery and leverage clinically de-risked tissue targets
Prioritize
Meaningful Opportunities
Major unmet needs where RNA editing can really do something unique
Core Focus area
Korro Bio is creating transformative therapeutics
for patients by selectively editing messenger RNA to recode specific codons to deliver a beneficial change in protein sequence, structure and function.
Our foundational technology holds the promise
to provide an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms.
THERAPEUTIC INDICATIONS
are prioritized across tissues where safe and targeted editing of messenger RNA could provide unique benefits over other modalities in development.
Core Focus Areas
We are seeing big potential with our technology to make a
significant impact in the following therapeutic areas.
LIVER (HEPATOCYTE)
Well-established delivery for oligonucleotides and AAV, robust adenosine deamination activity
CNS (NEURON)
Main tissue expressing ADAR2 and primary site of endogenous action, precedented IT delivery
RETINA
Potential to target neuronal population in back-of-eye (photoreceptor/RGC)
OTHERS
Kidney, lung, and muscle may support editing with appropriate delivery technologies
Korro Team
We are seeing big potential with our technology to make a
significant impact in the following therapeutic areas.
Korro Team
Join Our Team
We are seeing big potential with our technology to make a
significant impact in the following therapeutic areas.
The above positions not an exact match but think you could contribute in other ways?
Contact us below to tell us what you do. We’re always keeping an eye out for exceptional talent!
Contact Us
Get in touch for investment, partnership, or career inquiries; or to learn more about our technology and pipeline.
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KORRO BIO, INC.
400 Technology Square, ​10th Floor
Cambridge, MA  02139
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