Company
Korro Bio is a privately held biotechnology company launching out of a top-tier life science venture firm headquartered in Cambridge, Massachusetts. We are utilizing the precision provided by nucleic acid-based therapeutics to target the sequences responsible for inherited disorders within the genetic code. At Korro Bio, our aim is to bring transformative treatments to patients with rare and debilitating diseases by addressing the underlying genetic cause.

We are committed to investing in the personal and professional growth of our employees by putting work-life balance, family values and expanding an employee’s knowledge at the forefront. This has helped to shape us into an energetic, inclusive and innovative team where your value is celebrated no matter your role.  Together we intertwine our positive culture and intrinsic motivation with our passion for advancing science to directly impact the future of RNA editing one letter at a time.
Position Summary
Korro Bio is seeking a motivated and experienced Scientist to join our team. Reporting to the Head of Target Biology, the Scientist will have the opportunity to work with an enthusiastic team of highly skilled scientists in a dynamic, high growth company. The successful candidate will be responsible for developing and carrying out disease models for liver diseases using both in vitro and in vivo systems.
Position Type
Full-time, Onsite Only
Responsibilities
  • Work with the Target Biology team to plan a model strategy for liver diseases identified by Korro’s target using in vitro systems as well as genetic and induced liver disease animal models.
  • Conduct experiments to determine the safety and efficacy of novel compounds in models across a range of liver disease indications.
  • Provide overall in vitro, invivo and ex vivo technical support for projects working to advance one or more experimental therapeutic compounds.
  • Responsible for carefully documenting research and effectively communicating results across teams.
  •  Build a therapeutic area team to support development of treatments for liver disease.
Qualifications
  • PhD.  with 6-10 years' experience in the biotechnology or pharmaceutical industry or academic equivalent with a focus onliver disease.
Other Knowledge, Experience, and Skills
  • Knowledge of tissue processing and molecular biology methods (RNA purification, PCR, qPCR, sequencing, and western blot).
  • Experience in differentiating iPSCs,creating organoids and other in vitro organ model systems (liver on a chip) to model human liver diseases in the laboratory
  • Experience running mouse models,including mouse handling, health monitoring, dosing and working with models of liver disease is highly desired.
  • Skilled in various methods of dosing (IV, SC and IP), blood collection (tail vein/submandibular and cardiac puncture) and multiple tissue collection at necropsy for subsequent ex vivo analysis.
  • Experience in using oligonucleotide compounds in vitro and in vivo (i.e. siRNA, antisense) is a plus.
  • Desire and drive to learn and understand the basic biologic mechanisms underpinning our products.
  • Exposure to utilizing software such as Graph Pad Prism, Microsoft office, Excel, and electronic laboratory notebooks for data analysis and data summary.
  • Excellent organizational, time management and data recording skills.
  • Experience managing research associates and scientists is a plus.
  • Experience in drug discovery and development through IND is a plus.
  • Able to thrive in a highly collaborative, fast-paced, team-oriented environment with colleagues from diverse disciplines.
  • Effective verbal and written communication skills.
  • Detail-oriented and excellent problem-solving abilities.
EEOC Statement
Korro Bio believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Korro Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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Senior Scientist- Liver Disease
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Other Open Positions
We are seeing big potential with our technology to make a
significant impact in the following therapeutic areas.
The above positions not an exact match but think you could contribute in other ways? Contact us below to tell us what you do — maybe we can make something work.  We’re always keeping an eye out for exceptional talent!
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KORRO BIO, INC.
400 Technology Square, ​10th Floor
Cambridge, MA  02139
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