Our approach

One letter. One edit.
A world of difference.

RNA editing holds great promise to rewrite what’s possible for patients. Since the discovery of the first generation of editing technologies, researchers have been working to overcome the inherent complexity of these initial approaches to develop viable new treatments for patients.

Our foundational platform for RNA editing – Oligonucleotide Promoted Editing of RNA (OPERA) – is inspired by the elegance and simplicity of the natural processes that many species, including humans, use to make transient, reversible changes to genetic instructions.